Rosie O'Donnell has dropped a significant amount of weight in recent years. But the star remembers when another A-lister recommended she drop some weight.
O'Donnell, 64, revealed that beloved director Penny Marshall urged her to “lose 20 pounds” on the set of the iconic 1992 baseball film, A League of Their Own.
“On League of Their Own, Penny Marshall didn’t help by saying, ‘Rosie, I want you to lose 20 pounds.’ I’m like, ‘You think I carry it around for fun, Penny?'” O’Donnell remembered telling the director, she told People. “When I look back, I go, ‘God, I wish I could have enjoyed the size I was.'”
Now with significant weight loss under her belt, O'Donnell recalled battling her weight.
“It’s very strange to just buy a pair of jeans that fit. When I would do late-night, my biggest concern wasn’t my set — it was, did I look fat?”
O'Donnell Had a Facelift
O'Donnell recently took to her Substack page to share a deeply personal essay about how she previously vowed never to have plastic surgery. However, she had a change of heart earlier this year when she decided to have a lower deep plane facelift.
“I used to feel very strongly about facelifts,” O’Donnell wrote on Substack. “Not casually — morally. I had assigned myself as head of all women who would never – ever. I thought it was a betrayal. Of feminism. Of aging. Of our team of women worldwide. And then I lost 50 pounds.”
Feeling like gravity was getting the best of her after her dramatic weight loss, O’Donnell would look in the mirror and say, “This isn’t aging, this is melting with intention.” Her 13-year-old child, Clay, didn’t like the idea of plastic surgery, telling O’Donnell she “earned her wrinkles.” While she put off the procedure for months, she finally went under the knife in January.
O’Donnell shared a photo of her results on Instagram.
O’Donnell’s Weight Loss Transformation
In the last couple of years, O’Donnell has been open about her 50-pound weight loss as a result of using Mounjaro. She went into more detail in a March 2025 TikTok video, sharing why she had started taking the medication. She also noted that, in addition to starting the medication to deal with her health issues, she had been spending more time cooking for her child, Clay.
“I’ve lost more weight. I am on Mounjaro for my diabetes and one of the side effects is you lose weight,” she explained. “But it’s also because I had a chef for over two years in Los Angeles and I don’t have a chef now. It’s me cooking for Clay and me.”