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For running backs, one of the biggest tells of future fantasy success lies in their offensive line.
Even the league’s most talented players can struggle behind inconsistent blocking, while a great line can turn average runners into fantasy paydays. Strong play in the trenches can create consistent rushing lanes, extend drives, and ultimately make life easier for those who run between them. And sometimes, that’s all it takes for an overlooked back to become a fantasy star.
If you’re looking for running backs with the best opportunity to exceed expectations in 2026, start with these players behind the league’s top offensive lines.
Omarion Hampton, Los Angeles Chargers
Fantasy managers are already betting big that Omarion Hampton (#12 ADP, #9 among RBs) will take a major leap in 2026.
Despite appearing in just nine games during his rookie season for the Chargers, Hampton still flashed his potential with 545 rushing yards, 32 receptions, and four touchdowns. However, an ankle injury suffered in Week 5 significantly hurt his production. Before the injury, Hampton averaged 16 fantasy points per game through Week 4; afterward, he hit the 20s just once for the remainder of the season.
It’s also important to note that some of Hampton’s best linemen were virtually nonexistent for the 2025 season. Rashawn Slater missed the entire season due to a torn patellar tendon, and Joe Alt appeared in just six games before multiple ankle injuries derailed his season.
